Description

O₂ Control Cabinet for InVitro Studies (Microaerophilic / Hypoxic)

For Cell Cultures

The Coy InVitro Hypoxic Cabinet System is the only system of its type that is a hermetically sealed chamber and allows continuous control of oxygen. The system features result in less gas consumption (lower operating cost) and more reproducible oxygen results when compared to tri-gas incubators and other cabinet systems. InVitro cabinets are designed to use existing lab incubators for temperature control while completely controlling oxygen levels (and optionally, CO₂) inside the cabinet.

Coy InVitro Cabinet Systems feature:

• Premixed tanks of N₂ and CO₂ gas with O₂ controller — Enables you to deliver CO₂ in multiple ways dependent upon your research and budget.
• Coy automatic CO₂ control system — Allows for precise control and constant digital monitoring of CO₂ gas inside the cabinet.
• Intermittent hypoxia — For dynamic O₂ cycling.
• High accuracy calibration kit — Enables calibration and mounting of the O₂ sensor.

Custom Sizing Options

Though this cabinet comes in four standard-size units, we can economically custom size or configure a cabinet to your lab needs. With modular designs and accessories, and 40 years of in-house customization experience, Coy is flexible in its problem solving approach.

The importance of oxygen levels in various biological processes has become increasingly significant to researchers. To study this requires consistent atmospheric control maintaining hypoxia, normoxia, hyperoxia, or anoxia to mimic physiological conditions. Coy offers a complete line of glove boxes and cabinets that enable you to maintain desired levels of CO₂, temperature and humidity, along with oxygen control. Our modular design allows us to configure systems, including custom designs, to meet your needs whether for tissue culture or live animal studies.

Periods of tissue hypoxia also develop in organs affected by atherosclerotic narrowing of nutritive arteries, during physical exercise and during acclimation to high altitude (Roels et al. 2007; Mounier et al. 2009).

Intermittent hypoxia has also been observed in rapidly growing tumors (Bhaskara et al. 2012), patients suffering from sickle cell anemia (Alexy et al. 2010) as well as in organs of premature infants (Poets et al. 1994; Stokowski 2005).